中国有色金属学报(英文版)
Transactions of Nonferrous Metals Society of China
| Vol. 33 No. 5 May 2023 |
（1. School of Materials and Energy, Southwest University, Chongqing 400715, China;
2. Chongqing Key Laboratory of Soft-matter Material Chemistry and Function Manufacturing, Southwest University, Chongqing 400715, China;
3. School of Food Science, Southwest University, Chongqing 400715, China;
4. Department of Clinical Laboratory, University-Town Hospital of Chongqing Medical University, Chongqing 401331, China）
Abstract:The commercial zinc aluminum alloy (ZA6-1) surface was functionalized with poly-(lactic-co-glycolic) acid (PLGA) containing sodium dodecyl sulfate (SDS) and levulinic acid (LA) for gaining antibacterial activity. A polymerized 3-aminopropyltriethoxysilane (APTES) layer was initially fabricated on the surface of ZA6-1 alloy to gain amino group, and the PLGA mixed with SDS/LA was subsequently immobilized on the as-treated surface through the electrostatic interaction between amino group and carboxyl group. The PLGA-SDS/LA coating on zinc alloy showed extremely good corrosion resistance with the degradation rate of 0.005 mm/a, which can be adjusted by varying the coating thickness. Furthermore, besides the good biocompatibility to osteoblasts, the PLGA-SDS/LA coating exhibited excellent antibacterial property, and the bactericidal rates against Staphylococcus aureus and Escherichia coli were 98.9% and 99.8%, respectively.
Key words: zinc alloy; polymer coating; antibacterial property; biocompatibility; corrosion behavior
