Transactions of Nonferrous Metals Society of China The Chinese Journal of Nonferrous Metals

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中国有色金属学报(英文版)

Transactions of Nonferrous Metals Society of China

Vol. 28    No. 7    July 2018

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Surface topography and cytocompatibility of metal injection molded Ti-22Nb alloy as biomaterial
Da-peng ZHAO1,2, Yu-kai CHEN1, Ke-ke CHANG3, Thomas EBEL2, Bérengère J C LUTHRIGNER-FEYERABEND2, Regine WILLUMEIT-R?MER2, Florian PYCZAK2

1. College of Biology, Hunan University, Changsha 410082, China;
2. Institute of Materials Research, Helmholtz-Zentrum Geesthacht, 21502 Geesthacht, Germany;
3. Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China

Abstract:Metal injection molding (MIM) was applied to fabricating Ti-22Nb (mass fraction, %) and commercially-pure Ti (CP-Ti, selected as reference) discs. As references, arc-melted and polished Ti-22Nb discs were employed. The surface topography and cytocompatibility were comparatively assessed on each configuration by microscopic analysis using confocal laser scanning microscopy and scanning electron microscopy and adhesion and viability tests. The results reveal that micron-scale roughness could be obtained via MIM process, and using blended Ti and Nb elemental powders instead of only Ti powder as raw materials leads to much higher surface roughness and surface area ratio. None of the three materials shows cytotoxicity, and the adhesion of human primary cells seems to be increased on the MIM Ti-22Nb specimens, especially around the closed-pores on the surface.

 

Key words: metal injection molding; Ti-Nb alloy; surface topography; cell adhesion; cell proliferation

ISSN 1004-0609
CN 43-1238/TG
CODEN: ZYJXFK

ISSN 1003-6326
CN 43-1239/TG
CODEN: TNMCEW

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