中国有色金属学报(英文版)
Transactions of Nonferrous Metals Society of China
| Vol. 26 No. 1 January 2016 |
（1. Department of Conservative Dentistry and Periodontology, Poznan University of Medical Sciences,
Bukowska 70, Poznan 60-812, Poland;
2. Faculty of Pharmacy, Department of Genetics and Pharmaceutical Microbiology,
Poznan University of Medical Sciences, Swiecickiego 4, Poznan 60-781, Poland;
3. Division of Mother’s and Child’s Health, Poznan University of Medical Sciences, Polna 33, Poznan 60-535, Poland;
4. Institute of Materials Science and Engineering, Poznan University of Technology,
Jana Pawla II 24, Poznan 61-138, Poland;
5. Institute of Human Genetics, Polish Academy of Sciences, Strzeszynska 32, Poznan 60-479, Poland）
Abstract:Mechanical alloying and annealing at 1150 °C for 2 h under an argon atmosphere were used to prepare Ti-45S5 bioglass nanocomposites. Ti-45S5 bioglass material was chemically modified by silver. The antibacterial activity of Ti-10% 45S5 bioglass nanocomposite containing silver against Streptococcus mutans and Staphylococcus aureus was studied. Nanocomposites were characterized by X-ray diffraction, scanning electron microscopy equipped with an electron energy dispersive spectrometer and transmission electron microscopy to evaluate phase composition, crystal structure and grain size.In vitro bacterial adhesion study indicated a significantly reduced number of Streptococcus mutans and Staphylococcus aureus on the bulk nanostructured Ti-45S5 bioglass-Ag plate surface in comparison to that on microcrystalline Ti plate surface. Nanostructured Ti-based biomaterials can be considered to be the future generation of dental implants.
Key words: 45S5 bioglass;antimicrobial activity; silver; titanium; dental implant; Streptococcus mutans; Staphylococcus aureus
