(1. 西北工业大学 凝固技术国家重点实验室，西安 710072；
2. 西北工业大学 生命科学学院，西安 710072)
摘 要: 由于预钙化对HA有诱导沉积作用，进而形成均匀涂层，而未预钙化的多孔钛表面由于表面张力作用形成团簇状HA涂层。采用碱热处理+模拟体液(SBF)等化学方法在多孔钛表面制备羟基磷灰石(HA)涂层，采用扫描电镜观察多孔钛表面形貌，采用能谱分析仪对表面的HA涂层成分进行分析，对比研究预钙化对HA形貌的影响，并探讨不同形貌HA的形成机理。结果表明：采用预钙化处理的多孔钛表面形成均匀附着且有一定厚度的HA，而未预钙化多孔钛表面则形成以团簇状不均匀分布的HA。
关键字: 多孔钛；碱热处理；预钙化；团簇；羟基磷灰石
（1. State Key Laboratory of Solidification Processing, Northwestern Polytechnical University, Xi’an 710072, China;
2. School of Life Science, Northwestern Polytechnical University, Xi’an 710072, China）
Abstract:The formation of HA is induced by pre-calcified, leading to form a uniform coating. However, because of the effect of surface tension, cluster-like HA is formed. A hydroxyapatite (HA) coating on the porous titanium surface was prepared by NaOH heat treatment and heat treatment followed by immersing into the simulated body fluid (SBF). The influence of pre-calcified on HA morphology and element content was studied, the formation mechanisms of HA with different morphologies were explored. The results show the hydroxyapatite of porous titanium surface after pre-calcified is attached uniformly and has a certain thickness. However, the hydroxyapatite without pre-calcified is unevenly distributed on porous titanium surface in clusters.
Key words: porous titanium; NaOH heat treatment; pre-calcification; cluster-like; hydroxyapatite
