Transactions of Nonferrous Metals Society of China The Chinese Journal of Nonferrous Metals

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中国有色金属学报(英文版)

Transactions of Nonferrous Metals Society of China

Vol. 22    No. 12    December 2012

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Mechanism of anti-arterial thrombosis of Dahuangzhecong Fang screened by Ti-Al intermetallic compound porous material
WAN Ling1, WANG Zhan-yi2, WEI Xing1, LI Ji-yang1, ZHONG Guang-wei1,
DUAN Xiao-peng3, HE Fu-yuan3, JIANG Yao4

1. Xiangya Hospital, Central South University, Changsha 410008, China;
2. Henan Yuzhou Chinese Medicine Hospital, Yuzhou 461670, China;
3. Hunan Traditional Chinese Medicine University, Changsha 410208, China;
4. State Key Laboratory for Powder Metallurgy, Central South University, Changsha 410083, China

Abstract:The mechanism of antithrombotic of Dahuangzhechong Fang separated and purified by Ti-Al intermetallic compound porous material (TAICPM) was researched. Dahuangzhechong Fang, which was isolated and screened by TAICPM, was used to oral rats. At the end of study, their blood and thrombus were collected. The results show that TAICPM with the pore size of 1-5 μm can screen Dahuangzhechong Fang well. Dahuangzhechong Fang can increase 6-keto-PGF1α, lower content of TXD2 and platelet. Dahuangzhechong Fang has good effect to resist arterial thrombosis.

 

Key words: Ti-Al intermetallic compound porous materials; Dahuangzhecong Fang; arterial thrombosis; isolated Chinese medicine

ISSN 1004-0609
CN 43-1238/TG
CODEN: ZYJXFK

ISSN 1003-6326
CN 43-1239/TG
CODEN: TNMCEW

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