中国有色金属学报(英文版)
Transactions of Nonferrous Metals Society of China
| Vol. 21 Special 2 August 2011 |
（1. Stomatology Hospital, Harbin Medical University, Harbin 150001, China;
2. State Key Laboratory of Robotics and System, Harbin Institute of Technology, Harbin 150080, China）
Abstract:The in-vitro degradation and in-vitro cytotoxicity of the as-extruded Mg-4.0Zn-0.2Ca alloy were investigated. The in-vitro corrosion tests indicate that Zn and Ca elements can dramatically increase the corrosion potential of the as-extruded Mg-4.0Zn-0.2Ca alloy in the simulated body fluid and reduce the degradation rate. The cytotoxicity of the as-extruded Mg-4.0Zn-0.2Ca alloy examined by MTT tests on L929 cells suggest that the alloy has eligible toxicity for implant applications.
Key words: magnesium alloy; biodegradation; biocompatibility; cytotoxicity
