中国有色金属学报(英文版)
Transactions of Nonferrous Metals Society of China
| Vol. 33 No. 8 August 2023 |
（1. College of Biomedical Engineering, Taiyuan University of Technology, Taiyuan 030024, China;
2. Shanxi Key Laboratory of Biomedical Metal Materials, College of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, China;
3. Shanxi Key Laboratory of Bone and Soft Tissue Injury Repair, Department of Orthopedics, Second Hospital of Shanxi Medical University, Taiyuan 030001, China;
4. Special Equipment Safety Supervision Inspection Institute of Jiangsu Province, National Graphene Products Quality Inspection and Testing Center (Jiangsu), Wuxi 214174, China）
Abstract:Graphene quantum dots (GQDs) were incorporated into TiO2 nanorods (TiO2 NR) by hydrothermal treatment to prevent bacterial infections of Ti implants. The successful preparation of TiO2 NR doped with GQDs on Ti was confirmed by scanning electron microscopy, high-resolution transmission electron microscopy, atomic force microscopy, X-ray photoelectron spectroscopy, X-ray diffraction and Fourier transform infrared spectrometer. Results showed that the mean diameter of the nanorod was 60 nm, and the hydrophilicity was significantly improved. The GQDs-modified TiO2 NR showed excellent antimicrobial effect against Streptococcus mutans with an efficiency of 97.8% due to the combined effect of GQDs and nanorod structure. Moreover, GQDs-modified TiO2 NR exhibited good biocompatibility and osteogenetic potency for cell spreading, thus contributing to the new bone formation even in bacteria-induced implant infection.
Key words: graphene quantum dots; nanorod; titanium; antibacterial property; osseointegration
